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目的研究头孢他啶和双黄连注射液、热毒宁注射液、喜炎平注射液联合应用抗临床分离的铜绿假单胞菌的效果。方法收集并分离临床来源的68株铜绿假单胞菌，采用微量棋盘稀释法，计算头孢他啶分别和3种中药制剂的FIC指数。结果采用头孢他啶和热毒宁注射液联用，以相加(11.76%)和无关(58.82%)作用为主，以协同(10.29%)和拮抗(8.82%%)为次。采用头孢他啶和双黄连注射液联用，以无关(36.76%)和相加(20.59%)作用为主，以协同(11.76%)和拮抗(16.18%)为次。头孢他啶与喜炎平注射液联用抗铜绿假单胞菌无效。结论在临床治疗过程中，可以佐以中药制剂以增强抗菌药物治疗的有效性。“,”Objective To study the ef ect of antibacterial action combined with ceftazidime and Shuanghuanglian injection, Reduning injection, Xiyanping injection on Pseudomonas Aeruginosa. Methods To col ect and isolate the 68 strains of Pseudomonas Aeruginosa in clinical, the fractional inhibitory concentration index was calculated with microdilution checkerboard method, about ceftazidime and Shuanghuanglian injection, Reduning Injection, Xiyanping Injection. Results The ef ect of antibiotics combination of ceftazidime and Reduning Injection was 11.76% additive and 58.82% independent action, while 10.29% was synergistic ef ect and 8.82% was antagonistic ef ect. The ef ect of antibiotics combination of ceftazidime and Shuanghuanglian Injection was 20.59%additive and 36.76% independent action, while 11.76% was synergistic ef ect and 16.18% was antagonistic ef ect. It is inef ective for us to combine ceftazidime with Xiyanping injection. Conclusion In the clinical course of treatment, chinese medicine preparation can be used to enhance the ef ectivenes of antimicrobial therapy.