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目的观察厄贝沙坦、倍他乐克对高血压病左室肥厚及心功能改善的疗效。方法对88例原发性高血压病合并左心室肥厚的病人口服厄贝沙坦150～300mg/d,倍他乐克6.25～100mg/d,共16W,治疗前测量血压及行心脏彩超检查,治疗过程中于第8周、16周复查心脏彩超,并定期监测血压。结果所有病例患者血压明显下降,基本达正常范围,对逆转左室肥厚及改善心功能有明显疗效,长期服用效果理想,副作用少。
Objective To observe the effect of irbesartan and metoprolol on hypertensive left ventricular hypertrophy and improvement of cardiac function. Methods 88 patients with essential hypertension complicated with left ventricular hypertrophy were treated with irbesartan 150 ~ 300mg / day and metoprolol 6.25 ~ 100mg / d for 16W. Before treatment, blood pressure and cardiac ultrasonography were examined. The course of treatment at the eighth week, 16 weeks review of echocardiography, and regular monitoring of blood pressure. Results All cases of patients with blood pressure decreased significantly, up to the normal range, to reverse left ventricular hypertrophy and improve cardiac function have a significant effect, long-term use with satisfactory results, fewer side effects.