目的 寻找正常前列解剖、组织学结构与年龄的变化规律。方法 分别取胎龄6个月～80岁尸体前列腺标本88例,按年龄分组,测其重量、体积、并通过光学显微镜观察组织结构的变化。结果 重量:10岁前4g;10岁为12g;20岁为18g;30岁为20g;40岁为23g;50岁为25g;60岁为26g;70岁为25g。结缔组织占百分比:10岁前29.6％;10岁为30.2％;20岁为32.1％;30岁为36.4％;40岁为39.7％;50为39.6％;60为35.3％;70为38.7％。结论 正常前列腺重量、体积在30岁前增长明显,30岁后增长缓慢。重量与体积呈正相关,前列腺比重接近1,结缔组织随年龄增加而增多。 Objective To find the normal foreline anatomy, histological structure and age changes. Methods 88 cases of fetal prostate specimens from 6 months to 80 years of gestation age were collected respectively. The weight and volume were measured by age group. The changes of tissue structure were observed by light microscope. Results Weight: 4g before 10 years old; 12g at 10 years old; 18g at 20 years old; 20g at 30 years old; 23g at 40 years old; 25g at 50 years old; 26g at 60 years old; 25g at 70 years old. The percentage of connective tissue: 29.6% before 10 years old; 30.2% at 10 years old; 32.1% at 20 years old; 36.4% at 30 years old; 39.7% at 40 years old; 39.6% at 50; 35.3% at 60; 38.7% at 70%. Conclusions Normal prostate weight and volume increased significantly before the age of 30, but slowly after the age of 30. Weight and volume were positively correlated, prostate proportion close to 1, connective tissue increased with age.