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目的:观察α-氰基丙烯酸正丁酯(NBCA)胶局部注射治疗咽、喉部血管瘤的疗效。方法:采用NBCA胶注射治疗咽、喉部血管瘤患者30例。手术在全身麻醉下进行,25例患者行气管切开术,在支撑喉镜下进行血管瘤内NBCA胶注射,NBCA胶与碘化油混合浓度为25.0%～33.33%,根据血管瘤大小,用胶量为0.5～2.0ml。病变局限于口咽且直径<1cm的5例患者未行气管切开术,在开口器下进行注射。术后用纤维喉镜观察不同时间血管瘤脱落情况。结果:瘤体直径<1cm者,1个月内完全脱落治愈;≥4cm者,脱落治愈时间延长至3.5个月。30例患者术后随访3个月～7年,均治愈,无血管瘤复发。结论:采用NBCA胶局部栓塞治疗血管瘤,可避免颈部切开治疗所造成的颈部创伤,减少颈部出血量,也避免了采用局部注射化疗药物治疗必须多次手术所造成的痛苦,是一种较安全有效的方法。
Objective: To observe the curative effect of local injection of n-butyl α-cyanoacrylate (NBCA) glue on pharynx and larynx hemangiomas. Methods: Thirty patients with throat and throat hemangiomas were treated with NBCA injection. The operation was performed under general anesthesia. Tracheotomy was performed in 25 patients. NBCA was injected into the hemangiomas under the support of the laryngoscope. The concentration of NBCA glue and iodized oil was 25.0% -33.33%. According to the size of the hemangioma, The amount of glue is 0.5 ~ 2.0ml. Five patients with lesions limited to the oropharynx and <1 cm in diameter had no tracheotomy and were injected under the mouth opener. Postoperative fibrolaryngoscope observation of hemangioma shedding at different times. Results: The tumor diameter less than 1cm, 1 month completely off cured; ≥ 4cm persons, shed healing time extended to 3.5 months. 30 patients were followed up for 3 months to 7 years, were cured, no recurrence of hemangiomas. Conclusion: NBCA glue partial embolization for the treatment of hemangiomas can avoid neck trauma caused by incision, reduce the amount of bleeding in the neck, but also to avoid the use of local injection chemotherapy drugs must be the result of multiple surgical pain caused by A safer and more effective method.