近年来,肿瘤标记物 CA19～9已广泛用于各种胃肠道恶性肿瘤的研究中,在评价胰腺癌的临床应用价值时可见敏感性是令人满意的,并与慢性胰腺炎的鉴别具有意义。在检测患有肝硬化和原发性肝细胞癌(HCC)并伴有肝硬化的病人血清中 CA19～9、AFP 含量进行鉴别诊断,测定中排除影响因素。在27例原发性肝细胞癌伴有或未伴有肝硬化的23例中测到高值的 AFP 敏感度达85％,而 CA19～9只测到12例具有高值的敏感度为 In recent years, tumor markers CA19-9 have been widely used in the study of various gastrointestinal cancers. When evaluating the clinical application value of pancreatic cancer, it can be seen that the sensitivity is satisfactory, and the identification of chronic pancreatitis has significance. The serum CA19-9 and AFP levels in patients with cirrhosis and primary hepatocellular carcinoma (HCC) associated with cirrhosis were used for differential diagnosis, and the influencing factors were excluded. In 27 cases of primary hepatocellular carcinoma with or without cirrhosis, the high sensitivity of AFP was 85%, while in CA19-9 12 cases had high sensitivity.