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目的总结我市2008年先天性甲状腺减低症(CH)筛查情况及部分影响因素分析,准确掌握我市CH筛查工作的现状,为下一步工作的提高提供依据。方法对我市2008年先天性甲低筛查工作进行回顾性调查,根据甲低患儿不同地域、性别等因素分析其患病的差异性。结果 1.2008我市共分娩新生儿45189例,其中38 149新生儿进行新生儿疾病筛查,筛查覆盖率达84.4%,确诊甲低患儿30例,发病率为0.79‰。2.株洲地区各县(市区)发病情况没有明显的差异性(P>0.05)。3.男女的发病率相当,没有明显的性别差异,这与有些报道中的男女比例1比2有一定的差异(1)。4.不同的居住地其发病情况没有显著性差异,但是发病率来看,农村较城镇高。结论通过对我市甲低筛查工作现状和发病差异性的分析,我们要进一步加大对筛查力度,提高筛查覆盖率,同时对其致病影响因素的分析,对高发地区加大宣传力度、普及CH筛查知识,医务工作者做好孕妇孕期指导,在医疗资源相对薄弱的农村要做好送医下乡,加大医疗投入,做好可预防因素的控制,降低甲低的发病率。
Objective To summarize the screening status and some influencing factors of congenital hypothyroidism (CH) in our city in 2008 and accurately grasp the current situation of CH screening in our city, and provide the basis for the further work. Methods A retrospective investigation was made on the screening of congenital hypothyroidism in our city in 2008, and the prevalence of hypothyroidism was analyzed according to different regions and genders. Results 1.2008 A total of 45189 newborn babies were delivered in our city, of which 38 149 newborns were screened for neonatal diseases with a screening coverage rate of 84.4%. Thirty children with confirmed hypothyroidism were diagnosed with the incidence of 0.79 ‰. There was no significant difference in the incidence of all counties (urban areas) in Zhuzhou (P> 0.05). 3. The incidence of men and women is comparable with no significant gender differences, which is somewhat different from the ratio of 1 to 2 in some reports (1). There is no significant difference in the incidence of different places of residence, but the incidence rate, rural areas than the town high. Conclusion Through the analysis of the status quo and incidence of hypothyroidism in our city, we should further increase the screening efforts to improve screening coverage, at the same time the analysis of the factors that affect its pathogenesis, and increase publicity in areas with high incidence Efforts to popularize CH screening knowledge, medical workers do pregnancy guidance during pregnancy, medical resources in rural areas should be relatively weak to send medical treatment to the countryside, increase medical input, preventable factor control, reduce the incidence of hypothyroidism rate.