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子宫肌瘤是最常见的妇科良性肿瘤,过去对超过妊娠12周大小的子宫肌瘤患者多选用子宫切除术或肌瘤剔除术。近年来的研究表明,子宫肌瘤的发生发展与孕激素有关。子宫能产生多种生物活性物质,并有内分泌功能,参与体内生殖、生理及病理过程,绝经前切除子宫者即使保留卵巢,也常引起更年期综合征、冠心病及骨质疏松症的提早出现,故采用药物治疗子宫肌瘤越来越引起人们的重视。为了解孕激素拮抗剂治疗子宫肌瘤的疗效,2007年3～12月对42例子宫肌瘤患者使用米非司酮治疗,效果较为满意,现报告如下。
Uterine fibroids are the most common benign gynecological tumors, the past more than 12 weeks of pregnancy size of the uterine fibroids patients choose hysterectomy or myomectomy. In recent years, studies have shown that the occurrence and development of uterine fibroids and progesterone. Uterus can produce a variety of bioactive substances, and have endocrine function, involved in reproductive, physiological and pathological processes, even if the premenopausal uterus to retain the ovaries, often lead to menopause syndrome, coronary heart disease and early osteoporosis, Therefore, the use of drug treatment of uterine fibroids more and more cause for attention. In order to understand the efficacy of progesterone antagonist treatment of uterine fibroids, from March to December 2007, 42 cases of uterine fibroids in patients with mifepristone treatment, the effect is more satisfactory, are as follows.