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目的:探讨不同剂量的孕激素治疗无排卵型月经失调的临床疗效。方法:将2012年3月~2014年3月本院收治的78例无排卵性月经失调患者,随机分为100mg/d(甲组)、200mg/d(乙组)、300mg/d(丙组)三种剂量的黄体酮治疗组,比较三组的临床治疗效果。结果:经过10天的治疗,甲组治疗总有效24例,有效率为92.3%,乙组和丙组治疗的总有效例数均为26例,有效率达到100%。甲组发生不良反应共2例,乙组发生不良反应3例,丙组发生不良反应4例。结论:不同剂量孕激素治疗无排卵性月经失调均取得了满意的疗效,在安全范围内剂量越大疗效越好,但不良反应发生率也越高。因此,在有效治疗量内,宜选取较低剂量进行治疗。
Objective: To investigate the clinical effects of different doses of progestin on anovulatory menstrual disorders. Methods: A total of 78 patients with anovulatory menstrual disorders admitted to our hospital from March 2012 to March 2014 were randomly divided into two groups: 100mg / d (group A), 200mg / d (group B) and 300mg / d ) Three doses of progesterone treatment group, the clinical efficacy of the three groups were compared. Results: After 10 days of treatment, the total effective rate in group A was 24.3%, the effective rate was 92.3%. The total effective number in group B and group C was 26, and the effective rate was 100%. There were 2 adverse reactions in group A, 3 in group B and 4 in group C. Conclusion: Different doses of progesterone treatment of anovulatory menstrual disorders have achieved satisfactory results, the larger the dose in the safety range the better the efficacy, but the higher the incidence of adverse reactions. Therefore, within the effective treatment, should choose a lower dose for treatment.