The three levels optimizing strategy is put forward for the networked manufacturing resources optimizing configuration, namely, the optimizing of a logical manufacturing process,the optimizing of simulation-based integration of process planning and scheduling, and the optimizing of networked production scheduling. Then, the web services-based architecture of networked manufacturing resources optimizing configuration is brought forward. Finally, the key algorithm of the networked manufacturing resources optimizing configuration is discussed, namely, the two phases manufacturing partners selection method, which including the group technology-based manufacturing resources pre-configuration and the genetic algorithm-based executable manufacturing process optimizing.