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目的探讨SARS(severeacuterespiratorysyndrome)患者综合治疗的血象变化,为治疗和防范提供指导意义。方法运用全自动血细胞检测仪CD3700,检测72例SARS患者治疗前后血象的变化,包括白细胞(WBC)、白细胞分类计数(DC)、红细胞(RBC)、血红蛋白(HB)等项目。结果SARS患者患病和治疗过程中观察发现,病人感染后经过2～12d潜伏期后发病,发病3～6d后,血象结果发生变化,出现明显WBC下降(P<0.01),中性粒细胞分类比例显著下降(P<0.01),淋巴细胞分类比例出现显著性增高(P<0.01),RBC、HB、以及RBC相关参数没有显著性变化(P>0.05);经抗菌、抗病毒类,并结合升白细胞治疗后,WBC有显著上升(P<0.01),WBC分类中,粒细胞比例增加,淋巴细胞比例降低,与治疗前有显著性差异(P<0.01)。结论SARS患者经综合治疗后的血象指标变化可以监测患病后病情的发展变化以及治疗效果观察,为临床诊断及预后效果等提供辅助指导意义。
Objective To investigate the changes of blood in patients with SARS (severeacuterespiratorysyndrome) and to provide guidance for treatment and prevention. Methods Blood samples were collected from 72 patients with SARS before and after treatment, including white blood cell (WBC), white blood cell count (DC), red blood cell (RBC) and hemoglobin (HB) using the CD3700 automatic blood cell analyzer. Results In the course of SARS patients’ illness and treatment, they found that after 2 ~ 12 days after the onset of infection, the blood results changed after 3 ~ 6 days of onset, and the WBC decreased significantly (P <0.01). The proportion of neutrophils (P <0.01), and there was no significant change in RBC, HB and RBC related parameters (P> 0.05). After antimicrobial, anti-virus and combined with L After WBC treatment, WBC increased significantly (P <0.01). In WBC classification, the proportion of granulocytes increased and the proportion of lymphocytes decreased, which was significantly different from that before treatment (P <0.01). Conclusion The changes of blood index after SARS patients can monitor the development and changes of the disease and the treatment effect after SARS patients provide auxiliary guidance for clinical diagnosis and prognosis.