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目的：严重的肾动脉狭窄病人常合并高血压病和肾功能损害，本研究评价PIRA后肾功能改变情况。方法：1995年4月至今，31例病人接受PTRA，手术动脉40支，9例为双侧肾动脉狭窄，共有37个支架，3例肾动脉狭窄是由肌纤维发育不良症所致，不需支架植入，病例按肾功能情况分为两组，A组12例，男6例，女6例，年龄59．1±17．7岁，血肌酐≤130μmol／L，平均102±17μmol／L。B组21例男16例，女3例，年龄69．9±7．8岁，血肌醉＞13μmol／L，平均254±126μmol／L。于术前、术后1周内及术后6个月分别测定血肌酐水平，15例PTRA病人术前作肾DTRA扫描。结果：所有PTRA及支架植入术均成功，无并发症。2例作为急救性PTRA病人（血肌酐分别为510μmol／L及455μmol／L）继续维持血透，其中一例二个月后死于败血症，随访6个月中其他29例病人均存活，无并发症或须外科手术，平均狭窄由83.0±9．4％降为3．4±9．4％，A组血肌酐水平术前及术后6个月无显著改变（98±25μmol／L比101±13μmol／L，和术前比P＝NS）。B组术后第一周有增高倾向，但无统计学意义（315±258μmol／L，和术前比P＝NS）。可是6个月随访与术前比较明显下降（205±109μmol／L，P＜0．05。15例行肾UTRA扫描（30支动脉）供评价，18支显著肾动脉狭窄（?
OBJECTIVE: Severe renal artery stenosis is often associated with hypertension and impaired renal function. This study evaluated changes in renal function after PIRA. METHODS: From April 1995 until now, 31 patients underwent PTRA with 40 arteries, 9 with bilateral renal artery stenosis and 37 with a total of 37 stents. Renal stenosis was caused by myofibrillar dysplasia in 3 patients without stent According to the renal function, the cases were divided into two groups. Group A consisted of 12 patients, 6 males and 6 females, aged 59.1 ± 17.7 years old with serum creatinine ≤130μmol / L with an average of 102 ± 17μmol / L. Group B, 21 males and 16 females, 3 females, aged 69.9 ± 7.8 years, blood drunk> 13μmol / L, an average of 254 ± 126μmol / L. Serum creatinine was measured preoperatively, within 1 week after surgery and 6 months after surgery. Fifteen PTRA patients underwent DTRA before surgery. Results: All PTRA and stenting were successful without complications. Two of the 2 patients with rescue PTRA (serum creatinine were 510μmol / L and 455μmol / L, respectively) continued to maintain hemodialysis. One patient died of septicemia two months later. The other 29 patients survived 6 months follow-up without complications Or surgery, the mean stenosis decreased from 83.0 ± 9.4% to 3.4 ± 9.4%. There was no significant change in serum creatinine level in group A before and after 6 months (98 ± 25μmol / L vs 101 ± 13μmol / L, and preoperative P = NS). There was a tendency of increase in the first week after operation in group B, but there was no statistical significance (315 ± 258 μmol / L, P = NS before operation). However, the 6-month follow-up was significantly decreased compared with the preoperative level (205 ± 109 μmol / L, P <0.05 for 15 cases). The renal allograft scan (30 arteries)