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目的探讨伽玛刀治疗各种类型颅内疾病的适应证、并发症的预防。方法3738例颅内疾病患者,男1877例,女1861例。其中颅内良性肿瘤(1698例)、颅内恶性肿瘤(1376例)、功能性疾病(285例)、血管病变(379例)。采用OUR-XGD型旋转式伽玛刀治疗,周边剂量为8~80Gy,等剂量曲线40%~90%,等中心点1~14个。结果3738例随访时间为3~120个月。各类疾病的有效率为,脑血管病变76.3%(289/379),良性肿瘤92.58%(1572/1698),恶性肿瘤85.39%(1175/1376),功能性疾病85.32%(246/258)。无伽玛刀治疗直接死亡。结论伽玛刀治疗颅内肿瘤、动静脉畸形及功能性疾病具有安全、有效、微创、并发症少等特点,是神经外科的主要治疗手段之一。
Objective To investigate the indications and complications of gamma knife in treating various types of intracranial diseases. Methods 3738 cases of intracranial disease patients, 1877 cases of males and 1861 females. Including benign intracranial tumors (1698 cases), intracranial malignancies (1376 cases), functional diseases (285 cases), vascular lesions (379 cases). Using OUR-XGD rotary gamma knife treatment, peripheral dose of 8 ~ 80Gy, isodose curve of 40% to 90%, such as the center of 1 to 14. Results 3738 cases were followed up for 3 to 120 months. The effective rates of various diseases were 76.3% (289/379) of cerebrovascular diseases, 92.58% (1572/1698) of benign tumors, 85.39% (1175/1376) of malignant tumors and 85.32% (246/258) of functional diseases. No gamma knife treatment died directly. Conclusion Gamma knife treatment of intracranial tumors, arteriovenous malformations and functional diseases with safe, effective, minimally invasive, less complications, is one of the main surgical treatment of neurosurgery.