抗r-氨基丁酸B(GABA-B)型受体脑炎是边缘性脑炎的一种,主要与细胞膜抗原抗体有关。GABA-B受体是G-蛋白偶联受体,属于抑制性突触蛋白,对神经递质传递和维持突触稳定性具有重要作用,广泛分布于中枢和外周神经系统;在中枢神经系统内以海马、丘脑和小脑的浓度最高~([1]),临床上,多数抗GABA-B受体脑炎患者以癫痫为主要起病状态, Anti-r-aminobutyric acid B (GABA-B) receptor encephalitis is a form of borderline encephalitis that is primarily associated with membrane antigen and antibody. GABA-B receptor is a G-protein coupled receptor belonging to the inhibitory syntrophic protein, plays an important role in the transmission of neurotransmitters and the maintenance of synaptic stability. It is widely distributed in the central and peripheral nervous systems; in the central nervous system The highest concentration of hippocampus, thalamus and cerebellum ~ ([1]), clinically, the majority of anti-GABA-B receptor encephalitis in patients with epilepsy as the main onset,