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目的探讨药物流产时加用米索前列醇,对药物流产的完全性和阴道出血情况的疗效观察。方法米非司酮配伍米索前列醇行药物流产。将2009年2月至2009年8月到本院就诊的120例停经≤49d,经B超确定为宫内妊娠要求药物流产的健康妇女,随机分为两组,研究组:60例,在药物流产的第三天(即流产的当天)上午阴道后穹隆放置米索前列醇200μg(1片),对照组60例不放置,两组病例均于流产后服用五加生化胶囊及抗生素7d。结果两组药物流产中:①完全流产率、不完全流产率情况:研究组与对照组分别为57例(95%),51例(85%)及3例(5%)、9例(15%)。两组完全流产率、不完全流产率差异具有统计学意义(P<0.05)。②平均出血天数:研究组为(5.32±3.51)d,对照组为(10.03±4.58)d,两组流产平均出血天数差异也具有统计学意义(P<0.05)。③出血量:研究组出血量明显少于对照组。结论药物流产时阴道后穹隆放置米索前列醇可明显提高药物流产的可靠性。
Objective To investigate the effect of adding misoprostol during medical abortion on the completeness of medical abortion and vaginal bleeding. Methods Mifepristone with misoprostol for medical abortion. From February 2009 to August 2009, 120 cases of menopausal dysmenorrhea ≤ 49 days who were admitted to our hospital and were confirmed as intrauterine pregnancy by medical ultrasound were randomly divided into two groups. The study group was 60 cases, On the third day after abortion (that is, the day of abortion), misoprostol 200 μg (1 tablet) was placed on the vaginal posterior fornix in the morning and 60 patients in the control group were not placed. Both groups were treated with biochemical capsules and antibiotics after abortion for 7 days. Results In the two groups of medical abortion, ①complete abortion rate and incomplete abortion rate were: 57 cases (95%), 51 cases (85%) and 3 cases (5%) in study group and control group %). Two groups of total abortion rate, incomplete abortion rate difference was statistically significant (P <0.05). ② The average number of bleeding days: the study group was (5.32 ± 3.51) d, the control group was (10.03 ± 4.58) d, the average number of days between the two groups was also statistically significant (P <0.05). The amount of bleeding: the study group was significantly less bleeding than the control group. Conclusion Medical misoprostol vaginal posterior forging misoprostol can significantly improve the reliability of medical abortion.