Katsnelson等识别出一种无编码蛋白的DNA区域仍能够决定表型的某些特征(身高、对某种疾病的易感)的机制。科学家们发现某些染色质的修饰常赋有表观遗传的意义,不受基因序列调节,事实上由个体的DNA决定。此外,这些染色质变异常伴有不同的单核苷酸多态性(SNP),提示此变异可能是使 Katsnelson et al. Identified a mechanism by which a region of DNA without coding protein still determines certain phenotypes (height, susceptibility to a disease). Scientists have found that certain chromatin modifications are often epigenetic, independent of the gene sequence and are in fact determined by the individual’s DNA. In addition, these chromatin abnormalities are accompanied by different SNPs, suggesting that this variation may be