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目的 :观察寿星宝对气虚、阴亏、血瘀证患者的记忆能力的临床疗效及实验研究结果。方法 :治疗组口服寿星宝并以口服还精煎为对照组 ,观察两组疗效及服药前后的抗氧化、血流变、TCD图谱变化 ,并进行了实验研究。结果 :治疗组(235例)改善记忆广度、瞬时记忆(P<0.01) ,并优于对照组(P<0.01)。视记忆两组均有改善 (P<0.01)。寿星宝提高超氧化物歧化酶 (SOD)、谷胱甘肽过氧化物酶(GSH -PX)、过氧化氢酶(CAT)活力 ,降低过氧化脂质 (Lpo)含量 ,改善全身血液流变性 ,增加脑供血量。结论 :寿星宝具有抗氧化作用 ,增加脑供血量 ,有利于促进机体记忆能力的增强和恢复作用。
Objectives: To observe the clinical efficacy and experimental findings of Shou Xing Bao on the memory abilities of patients with Qi Deficiency, Yin Deficiency, and Blood Stasis Syndrome. METHODS: The treatment group was treated with Shou-Shao-Bao and Oral Retort was served as the control group. The curative effect and the change of anti-oxidation, blood rheology, and TCD pattern before and after the treatment were observed and an experimental study was conducted. Results: The treatment group (235 cases) improved the memory span and transient memory (P<0.01), and was superior to the control group (P<0.01). Visual memory was improved in both groups (P<0.01). Shouxingbao increases superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), catalase (CAT) activity, reduces lipid peroxide (Lpo) content, and improves systemic hemorheology Increase brain blood supply. Conclusion: Shouxingbao possesses anti-oxidation effect and increases blood supply to the brain, which is beneficial to the enhancement of the memory function and recovery of the body.