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目的观察阿司匹林在心脑血管血栓性疾病患者治疗中的应用状况。方法选取医院收治的心脑血管血栓性疾病患者100例,随机分为观察组和对照组,每组50例。对照组接受常规性治疗,观察组在对照组治疗基础上给予阿司匹林药物治疗。观察比较2组治疗效果,观察用药期间不良反应发生情况,采用SF-36量表判定患者生活质量状况。结果观察组治疗总有效率为96.0%,高于对照组的82.0%(P<0.05);2组不良反应发生率比较(6.0%vs.8.0%)差异无统计学意义(P>0.05)。治疗后,观察组总体健康、身体疼痛、社会情感、心理状况、工作状况等项目评分均高于治疗前与对照组(P<0.01)。结论临床上治疗心脑血管血栓性疾病时可考虑给予阿司匹林药物治疗,疗效突出,不良反应少,安全可靠,抗血栓作用显著,值得推广应用。
Objective To observe the application of aspirin in the treatment of patients with cardiovascular and cerebrovascular thrombosis. Methods 100 cases of cardiovascular and thrombotic diseases admitted to hospital were randomly divided into observation group and control group, 50 cases in each group. Control group received routine treatment, the observation group was given aspirin based on the treatment of the control group. Observed and compared the treatment effect of 2 groups, observed the occurrence of adverse reactions during the treatment, using SF-36 scale to determine the quality of life of patients. Results The total effective rate in observation group was 96.0%, which was higher than that in control group (82.0%, P <0.05). There was no significant difference between the two groups (6.0% vs.8.0%) (P> 0.05). After treatment, the scores of items such as general health, body ache, social emotion, mental status and work status in the observation group were higher than those before treatment and the control group (P <0.01). Conclusions Aspirin can be considered in the treatment of cardiovascular and thrombotic diseases clinically. The curative effect is outstanding, the adverse reaction is less, the safety is reliable and the antithrombotic effect is significant, which is worth popularizing and applying.