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目的 :探讨住院患者念珠菌感染的种类及耐药现状。方法 :用法国生物 -梅里埃公司酵母菌鉴定系统和药敏试纸条进行菌株鉴定和药敏试验。结果 :白色念珠菌检出率最高 (5 0 .6 0 % ) ,热带念珠菌次之 (2 6 .5 1% ) ,高里氏念珠菌、近平滑念珠菌、分别为 9.6 4%和 7.2 3% ,其它念珠菌均在 5 .0 %以下。 6种抗真菌药中 ,5 -氟胞嘧啶、两性霉素B、制霉菌素的耐药率最低 (1.2 0 % ) ,唑类抗真菌的耐药率最高 (8.43～ 18.0 7% )。结论 :结果提示临床医师治疗真菌感染时应先进行培养和药敏试验 ,以便合理治疗 ,预防医院内感染。
Objective: To investigate the types of Candida infections and drug resistance in hospitalized patients. Methods: The strain identification and drug susceptibility test were carried out by the French bio-Merial Yeast identification system and the drug susceptibility test strips. Results: Candida albicans was the highest (60.0%), followed by Candida tropicalis (26.51%), Candida gurry and Candida parapsilosis were 9.64% and 7.2 3%, other Candida are below 5.0%. Of the 6 antifungal agents, 5 - flucytosine, amphotericin B and nystatin had the lowest resistance (1.2%) and azole antifungal (8.43-18.0 7%). Conclusion: The results suggest that clinicians should carry out culture and drug susceptibility tests before treatment of fungal infections in order to rationally treat and prevent nosocomial infections.