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采用对比方法 ,借助化学分析、表面形态分析及生物相容性表征技术等系统地研究了以活性炭纤维、表面改性活性炭纤维作为细胞固着化载体的表面特性及对微生物固着的影响。重点考察了纤维表面官能团、比表面积、润湿性等表面特性对微生物固着化的影响。研究结果表明 :(1)炭纤维表面的吸附特性对微生物的初期固着起着重要的作用 ,具有高比表面积的活性炭纤维更易于微生物固着并挂膜。 (2 )炭纤维表面润湿性与某些酸性官能团的适量增加 ,有益于载体表面微生物的固着。 (3)炭纤维尤其是活性炭纤维较市售有机高分子材料具有更加优异的生物相容性 ,前者的微生物固着化速率是后者的 4倍~ 16倍
By means of comparative methods, the surface properties of activated carbon fibers and surface-modified activated carbon fibers as the carrier for cell immobilization were investigated systematically by chemical analysis, surface morphology analysis and biocompatibility characterization techniques. Focuses on the fiber surface functional groups, specific surface area, wettability and other surface properties of microbial immobilization. The results show that: (1) The adsorption characteristics of carbon fiber surface plays an important role in the initial fixation of microorganisms. Activated carbon fibers with high specific surface area are easier to fix by microorganisms and hang on the membrane. (2) The surface wettability of carbon fiber increases with the amount of some acidic functional groups, which is beneficial to the immobilization of microorganisms on the carrier surface. (3) Carbon fiber, especially activated carbon fiber, has more excellent biocompatibility than the commercially available organic macromolecule materials. The former has 4 times to 16 times higher rate of microbial immobilization