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目的探讨肺癌患者下呼吸道感染的现状及危险因素。方法选择2009年11月至2011年10月收治的肺癌患者110例,观察患者是否发生下呼吸道感染,分析患者性别、年龄、吸烟史、肺癌分期、住院时间、侵入性操作、抗生素应用是否为下呼吸道感染发生的危险因素。结果 110例肺癌患者发生下呼吸道感染者71例,发生率为64.5%,以革兰阴性菌感染为主,其发生明显受到患者年龄、吸烟史、肺癌分期、住院时间、侵入性操作、抗生素应用的影响(P<0.05)。结论肺癌患者的年龄、吸烟史、肺癌分期、住院时间、侵入性操作、抗生素应用均为发生下呼吸道感染的危险因素,临床工作中应该针对可干预的危险因素采取有效的预防措施,提高患者的生活质量。
Objective To investigate the status and risk factors of lower respiratory tract infection in patients with lung cancer. Methods A total of 110 patients with lung cancer who were admitted from November 2009 to October 2011 were enrolled in this study. The patients were observed for lower respiratory tract infection, and their gender, age, smoking history, stage of lung cancer, hospitalization time, invasive procedure and antibiotic application were analyzed. Risk factors for respiratory infections. Results 71 cases of lower respiratory tract infection were found in 110 patients with lung cancer, the incidence rate was 64.5%. Gram-negative bacteria infection was the main cause of this disease. The occurrence was obviously affected by patient’s age, smoking history, lung cancer staging, hospitalization time, invasive operation and antibiotic application (P <0.05). Conclusion The age, smoking history, stage of lung cancer, hospitalization time, invasive operation and antibiotic application are the risk factors of lower respiratory tract infection in lung cancer patients. In clinical practice, effective precautionary measures should be taken to improve the risk factors of patients with lung cancer Quality of Life.