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应用双歧杆菌活菌制剂治疗肝硬化蛋白能量营养不良的患者。64例慢性乙型肝炎肝硬化患者随机分成两组,均给常规保肝、植物蛋白食谱治疗。治疗组加双歧杆菌制剂。对照组口服多酶片。8周后治疗组患者每日摄入蛋白质有显著增加;理想体重百分比、三头肌皮褶厚度、血清白蛋白测定值等变化与治疗前比较,有显著性差异(P<0.05)。对照组上述指标无明显变化。提示双歧杆菌通过抑制肠道菌群失调而促进营养吸收,阻止细菌易位,减少内毒素来源,减轻肝脏损害,有利于白蛋白合成。
Application of live bifidobacteria preparation for patients with cirrhosis and malnutrition. Sixty-four patients with chronic hepatitis B cirrhosis were randomly divided into two groups, all given conventional liver protection, plant protein diet therapy. Treatment group plus bifidobacterium preparations. The control group oral multi-enzyme tablets. After 8 weeks, the daily intake of protein in the treatment group increased significantly. The changes of the ideal body weight percentage, triceps skinfold thickness and serum albumin were significantly different from those before treatment (P <0.05). The control group no significant change in the above indicators. Prompted Bifidobacterium by inhibiting intestinal flora and promote nutrient absorption, prevent bacterial translocation, reduce the source of endotoxin, reduce liver damage, is conducive to albumin synthesis.