染色体数目及结构异常能够遗传给下一代 ,研究表明新生儿染色体异常发生率波动于0 4 7%～ 0 84% ,平均 0 .62 5 % [1] 。因此 ,开展医学细胞遗传学研究对于指导生育具有重大意义。现将我中心 1 995～ 2 0 0 0年门诊遗传咨询者的染色体分析如下。1　资料与方法1 .1资料来源 Chromosome number and structural abnormalities can be inherited to the next generation, studies have shown that the incidence of chromosomal abnormalities in newborns fluctuated between 047% ~ 0 84%, an average of 0.62 5% [1]. Therefore, to carry out the study of medical cytogenetics for the guidance of fertility is of great significance. The chromosome analysis of outpatient genetic counselors from 1995 to 2000 in our center is as follows. 1 Materials and Methods 1 .1 Source