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目的探讨肿瘤患者应用紫杉类药物后出现肌肉关节疼痛的发生率及其规律。方法便利抽取北京市某三级甲等专科医院131例输注紫杉醇后的肿瘤患者,采用自行设计的问卷进行调查,其中疼痛量表采用视觉模拟评分和0-10数字疼痛强度量表相结合。结果疼痛发生率为74.1%,其中轻度痛占61.9%,中重度痛占36.1%。结论应用紫杉类药物后出现肌肉关节疼痛具有普遍性和规律性,为指导患者进行药物止痛提供方向,以帮助患者提高生活质量。
Objective To investigate the incidence and regularity of muscle and joint pain in cancer patients after application of taxanes. Methods A total of 131 cancer patients after paclitaxel infusion in a tertiary hospital in Beijing were collected and investigated by self-designed questionnaire. The pain scale was visual analogue scale combined with 0-10 digital pain intensity scale. Results The incidence of pain was 74.1%, with mild pain accounting for 61.9% and moderate to severe pain accounting for 36.1%. Conclusion It is common and regular that muscle-joint pain appears after application of taxane, which will help guide the patients to provide medicine analgesia to help patients improve their quality of life.