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促胃肠动力药物是临床最常用的药物种类之一,其安全性一直倍受关注,其中有2个已上市多年的药物因安全性问题撤出市场。本文从药理作用、药动学及临床应用评价等方面对各种促胃肠动力药物的安全性作一综述。
Gastrointestinal motility drugs are one of the most commonly used types of drugs in clinical practice. Their safety has drawn great attention. Among them, two drugs that have been on the market for many years have been withdrawn from the market due to safety issues. This review summarizes the safety of various gastrointestinal motility drugs in terms of pharmacology, pharmacokinetics and clinical evaluation.