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目的:探讨风湿关节炎采用来氟米特联合甲氨蝶呤治疗的临床疗效。方法:回顾我院收治的风湿关节炎患者。随机平均分为对照组(甲氨蝶呤)和观察组(来氟米特联合甲氨蝶呤),比较2组治疗效果。结果:2组在治疗效果比较具有显著性差异,具有统计学意义;患者在治疗前后各项指标有显著性差异,P<0.05;2组患者在治疗后各指标结果比较,P<0.05,具有统计学意义。结论:来氟米特联合甲氨蝶呤治疗风湿关节炎,具有起效快,作用强等特点,能够缓解患者的症状和体征,改善病情,值得临床推广使用。
Objective: To investigate the clinical efficacy of leflunomide and methotrexate in rheumatoid arthritis. Methods: Review our hospital patients with rheumatoid arthritis. Randomly divided into control group (methotrexate) and observation group (leflunomide combined with methotrexate), the two groups were compared. Results: There was significant difference between the two groups in the treatment effect, with statistical significance; the indexes of the patients before and after treatment were significantly different (P <0.05); the results of the two groups after treatment were compared, P <0.05, with Statistical significance. Conclusion: Leflunomide combined with methotrexate treatment of rheumatoid arthritis, with rapid onset, strong effect and other characteristics, can alleviate the symptoms and signs of patients and improve the condition, worthy of clinical promotion and use.