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目的观察甘露醇加地塞米松治疗小儿急性感染性喉炎的疗效。方法选择2008年12月—2010年12月经诊断确诊为小儿急性感染性喉炎的120例患者。接受常规抗感染治疗同时行地塞米松静脉推注。地塞米松用量不改变,在安全范围下由少量到足量地静滴甘露醇。动态监测患者夜间平均心率、呼吸次数、咳嗽次数。结果随甘露醇静滴量增加,患者夜间心率异常,呼吸异常的发生率减少,同时咳嗽次数明显降低。结论甘露醇加地塞米松治疗小儿急性感染性喉炎中效果显著,减轻患者炎症方面尤为突出。故推荐甘露醇加地塞米松在治疗小儿急性感染性喉炎时作为辅助治疗的优选。
Objective To observe the efficacy of mannitol and dexamethasone in the treatment of children with acute infectious laryngitis. Methods 120 patients diagnosed as pediatric acute infectious laryngitis from December 2008 to December 2010 were selected. Routine anti-infective therapy was performed simultaneously with dexamethasone intravenous bolus. Dexamethasone dosage does not change, in a safe range from a small amount to a sufficient amount of intravenous infusion of mannitol. Dynamic monitoring of patients with average heart rate at night, respiratory rate, cough frequency. Results With the increase of intravenous drip of mannitol, patients had abnormal heart rate at night and the incidence of respiratory abnormalities decreased while the frequency of cough decreased significantly. Conclusion Mannitol plus dexamethasone treatment of children with acute infectious laryngitis significant effect, reduce inflammation in patients with particularly prominent. Therefore recommended mannitol plus dexamethasone in the treatment of acute respiratory laryngitis in children as adjuvant therapy preferred.