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目的探讨胰岛素不同用药途径在糖尿病患者晚间血糖及低血糖控制中的应用价值。方法糖尿病患者58例,采用随机对照分组法将患者分为对照组和观察组,各29例,其中对照组采用胰岛素行多次皮下注射治疗,观察组采用胰岛素泵治疗,观察两组患者夜间血糖控制情况以及低血糖的发生率。结果观察组患者晚餐前、睡前血糖分别为(5.76±0.58)mmol/L、(6.19±0.42)mmol/L低于对照组,凌晨2:00的血糖为(5.86±0.51)较对照组高,差异均具有统计学意义(P<0.05)。观察组低血糖发生率为3.45%低于对照组低血糖发生率24.14%,差异具有统计学意义(P<0.05)。结论利用胰岛素泵治疗糖尿病,能够降低低血糖的发生几率,值得推广应用。
Objective To investigate the value of different routes of insulin in the control of nighttime blood glucose and hypoglycemia in diabetic patients. Methods Fifty-eight patients with diabetes mellitus were divided into control group and observation group by randomized controlled grouping method, with 29 cases in each group. The control group received multiple subcutaneous injections of insulin and the observation group was treated with insulin pump. The nighttime blood glucose Control and the incidence of hypoglycemia. Results The blood glucose before going to bed and before going to sleep in the observation group was (5.76 ± 0.58) mmol / L, (6.19 ± 0.42) mmol / L respectively, lower than that in the control group, and the blood glucose was (5.86 ± 0.51) at 2:00 am , The differences were statistically significant (P <0.05). The incidence of hypoglycemia in observation group was 3.45%, which was lower than that in control group (24.14%), the difference was statistically significant (P <0.05). Conclusions The use of insulin pump in the treatment of diabetes, can reduce the incidence of hypoglycemia, it is worth promoting the application.