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目的:观察胺碘酮联合比索洛尔在冠状动脉旁路移植术(CABG)后心房颤动(AF)治疗中的应用价值。方法:抽取周口市中心医院2018年7月至2019年7月收治的70例CABG术后AF患者作为研究对象，采用随机数表法分为对照组和观察组，每组35例。两组均于CABG术后AF发病当天实施常规治疗，在此基础上，对照组于AF发病当天采用比索洛尔治疗，观察组于AF发病当天采用胺碘酮联合比索洛尔治疗。两组均治疗至AF结束，记录并比较两组比索洛尔用量；记录两组AF转窦性心律情况[AF起始时间、持续时间、最大心率(HR)及1 d内AF成功转窦性心律情况]；分别于治疗前及治疗后1 d比较两组治疗相关指标[心锚重复蛋白(CARP)及左房内径(LAD)]。结果:观察组比索洛尔用量少于对照组(n P0.05)；观察组AF持续时间短于对照组，最大HR低于对照组，1 d内AF成功转窦性心律患者占比高于对照组，差异有统计学意义(n P<0.05)；观察组治疗后CARP及LAD均低于对照组(n P均0.05)。n 结论:胺碘酮联合比索洛尔治疗CABG术后AF可减少比索洛尔用量，缩短AF持续时间，使患者HR快速恢复，在短期内AF转窦性心律成功率较高，且联合治疗不会增加不良反应发生，安全性好。“,”Objective:To observe the value of amiodarone combined with bisoprolol in the treatment of atrial fibrillation (AF) after coronary artery bypass grafting (CABG).Methods:A total of 70 patients with AF after CABG in Zhoukou Central Hospital from July 2018 to July 2019 were selected as the research objects, and they were divided into control group and observation group by random number table method, with 35 cases in each group. Both groups were given routine treatment on the day of AF onset after CABG. On this basis, the control group was treated with bisoprolol on the day of AF onset, and the observation group was treated with amiodarone combined with bisoprolol on the day of AF onset. Both groups were treated until the end of AF. And the dosage of bisoprolol was recorded and compared. The AF conversion to sinus rhythm was recorded in both groups, including AF start time, duration, the maximum heart rate (HR), and AF successfully converted to sinus within 1 day. Before and 1 day after treatment, the treatment-related indicators, such as heart anchoring repeat protein (CARP) and left atrium inner diameter (LAD), were compared between the two groups.Results:The dosage of bisoprolol in the observation group was less than that in the control group (n P0.05). Compared with the control group, the AF duration was shorter, the maximum HR was lower, and the proportion of patients with AF successfully converted to sinus rhythm within 1 day was higher in the observation group (n P<0.05). After treatment, CARP and LAD in the observation group were lower than those in the control group (n P0.05).n Conclusions:Amiodarone combined with bisoprolol in the treatment of AF after CABG can reduce the dose of bisoprolol, shorten the duration of AF, and make the patient’s HR recovered quickly. In the short term, the success rate of AF converting to sinus rhythm is higher, without increasing the occurrence of adverse reactions, and it has high safety.