报道小鼠感染日本血吸虫后肝脏成纤维细胞的体外培养及其形态学观察（光镜）。取感染后４２ｄ鼠肝经酶消化处理后，制备肝细胞悬液，经贴壁培养分离成纤维细胞。光镜下，培养中细胞多呈梭形、三角形、多角形外观，胞质突起较多，细长、透明，胞核一个，清晰可见。细胞增殖旺盛，可见明显分裂征象。 Report on in vitro culture and morphological observation of liver fibroblasts in mice infected with Schistosoma japonicum (light microscope). After 42 days of infection, the rat liver was digested by enzyme and the suspension of hepatocytes was prepared, and the fibroblasts were separated by adherent culture. Under light microscope, cells in culture mostly fusiform, triangular, polygonal appearance, cytoplasmic processes more, slender, transparent, a nucleus, clearly visible. Strong cell proliferation, showing obvious signs of division.