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目的:调查了解某医院新生儿中新鲜冷冻血浆(FFP)输注情况,为更好地指导新生儿输血治疗提供依据。方法:对2009年1月-2011年12月住院经输注FFP治疗的新生儿1095例的临床资料进行分析。结果:新生儿输注FFP占医院血浆输注总量的6.95%;输注FFP治疗病种以新生儿肺炎、呼吸窘迫和肺透明膜病居前3位。FFP输注前后,新生儿总胆红素、间接胆红素、血浆总蛋白和清蛋白水平差异不显著(P>0.05)。结论:FFP输注前后,仅检测了总胆红素、间接胆红素、血浆总蛋白和清蛋白等指标,未见凝血因子水平检查,在输注FFP时应加强对凝血因子水平的检查。
Objective: To investigate the fresh frozen plasma (FFP) infusion in neonates in a hospital and provide a basis for better guiding neonatal transfusion. Methods: The clinical data of 1095 newborns admitted to hospital from January 2009 to December 2011 with FFP were analyzed. Results: Infant FFP accounted for 6.95% of the total plasma infusion in hospital. Infants with FFP were the top 3 infants with neonatal pneumonia, respiratory distress and hyaline membrane disease. The levels of total bilirubin, indirect bilirubin, plasma total protein and albumin in neonates were not significantly different before and after FFP infusion (P> 0.05). Conclusion: Only the indexes of total bilirubin, indirect bilirubin, plasma total protein and albumin were detected before and after FFP infusion. No coagulation factors were detected. FFP should be checked for the level of coagulation factors.