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丙型肝炎病毒(HCV)是由10 kb核苷酸组成的单股正链RNA病毒,与输血后急、慢性肝炎、肝硬变、肝癌关系密切。丙型肝炎的特异诊断主要依据血清学特异抗体的检测,或进行反转录PCR直接检测丙型肝炎病毒核酸(HCV-RNA)。Fattevich等曾报道慢性乙型肝炎患者中的 HCV感染(J Infect Dis1991;163:400)。现报道丙型肝炎与HBV的重叠感染情况及其临床后果。
Hepatitis C virus (HCV) is a single-stranded positive-sense RNA virus consisting of 10 kb of nucleotides, which is closely related to acute and chronic hepatitis, liver cirrhosis and liver cancer after blood transfusion. Specific diagnosis of hepatitis C is mainly based on the detection of serological antibodies, or reverse transcription PCR for direct detection of hepatitis C virus nucleic acid (HCV-RNA). Fattevich et al. Have reported HCV infection in patients with chronic hepatitis B (J Infect Dis 1991; 163: 400). Now report the hepatitis C and HBV overlap infection and its clinical consequences.