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目的观察盐酸米诺环素软膏局部应用治疗牙周炎的临床效果。方法选取2013年6月-2014年6月接收并治疗牙周炎患者中随机抽取60例进行研究和分析,并将研究对象随机分为研究组和对照组各30例。2组患者在常规治疗的基础上,对照组加以碘甘油治疗,研究组加以盐酸米诺环素软膏局部治疗,对比2组患者治疗后的效果。结果研究组治疗总有效率为96.67%明显高于对照组的70.00%(P<0.05);2组治疗后的牙龈指数(GL)、牙周袋深度(PD)指标均低于治疗前指标(P<0.05);且研究组GL、PD指标下降较对照组更明显,差异均有统计学意义(P<0.05)。结论对于牙周炎患者,采用盐酸米诺环素软膏局部应用治疗的方式临床效果良好,是一种安全有效的药物。
Objective To observe the clinical effect of local application of minocycline hydrochloride ointment in the treatment of periodontitis. Methods From June 2013 to June 2014, 60 patients randomly selected from patients with periodontitis were studied and analyzed. The subjects were randomly divided into study group (30 cases) and control group (30 cases). The patients in two groups were treated with iodine glycerin on the basis of routine treatment. The study group was given local treatment with minocycline hydrochloride ointment, and the effect of the two groups was compared. Results The total effective rate of the study group was 96.67%, which was significantly higher than that of the control group (70.00%, P <0.05). After treatment, the indexes of gingival index (GL) and periodontal pocket depth P <0.05). The decrease of GL and PD index in the study group was more obvious than that in the control group (P <0.05). Conclusion For patients with periodontitis, the local application of minocycline hydrochloride ointment has a good clinical effect and is a safe and effective drug.