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目的:分析妊娠期对视神经脊髓炎的影响和治疗选择。方法:总结分析近年来妊娠期对视神经脊髓炎的影响和治疗选择的文章。结果和结论:视神经脊髓炎是一种中枢神经系统慢性自身免疫性疾病,主要发生在生育期女性。妊娠可以触发疾病发生或加重病情,疾病可以增加产科并发症风险,但绝大多数妊娠获得成功结果。妊娠期病情波动可以采用静脉大剂量甲基泼尼龙、免疫球蛋白、血浆交换等治疗,以及激素联合免疫球蛋白或血浆交换治疗。病情缓解至少半年后妊娠或许有利于母婴健康,分娩后恢复维持治疗有助于预防疾病复发。
Objective: To analyze the influence of pregnancy on optic neuromyelitis and treatment options. Methods: To summarize and analyze the influence and treatment options of optic neuromyelitis in pregnancy in recent years. RESULTS AND CONCLUSION: Optic neuromyelitis is a chronic autoimmune disease of the central nervous system that occurs mainly in women of reproductive age. Pregnancy can trigger or exacerbate the disease, the disease can increase the risk of obstetric complications, but the vast majority of pregnancy success. Vaginal fluctuations during pregnancy can be intravenous high-dose methylprednisolone, immunoglobulin, plasma exchange and other treatment, and hormone combination immunoglobulin or plasma exchange therapy. Pregnancy may be beneficial to maternal and child health after at least six months of remission and resuming maintenance after childbirth may help prevent recurrence of the disease.