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分泌性中耳炎(otitis media with effusion,OME)的动物模型研究始于上世纪二十年代,80余年来,其为人类逐步认识OME的病因、发病机制等提供了良好的研究手段。本文就文献中常用的OME动物模型及其造模方法作一综述。1动物选择动物的选择要根据研究目的、造模方法及实验条件而定。
The study of animal model of otitis media with effusion (OME) began in the 1920s. For more than 80 years, it has provided a good research method for human being to gradually understand the etiology and pathogenesis of OME. This article reviews the commonly used OME animal models in the literature and their modeling methods. 1 animal selection animal selection according to research purposes, modeling methods and experimental conditions may be.