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槲皮素给小白鼠ip(25或50mg/kg)引起小鼠脾脏和胸腺的重量显著减少,同时降低了嗜酸性粒细胞数及嗜中性粒细胞数。它也可以降低iv的碳廓清率,并抑制小鼠腹腔巨噬细胞对鸡红细胞的吞噬作用。实验证明,槲皮素ip(25或50mg/kg)抑制小鼠的PCA反应,也抑制致敏豚鼠肺释放过敏介质SRS-A和组胺。在整体实验中它可以对抗由SRS-A或组胺引起的豚鼠哮喘。
Quercetin caused mice ip (25 or 50 mg/kg) to cause a significant reduction in spleen and thymus weights, as well as a decrease in the number of eosinophils and neutrophils. It can also reduce the rate of carbon clearance of iv and inhibit the phagocytosis of chicken red blood cells by mouse peritoneal macrophages. Experiments have shown that quercetin ip (25 or 50 mg/kg) inhibits PCA responses in mice and also inhibits sensitized guinea pig lungs from releasing the allergic mediators SRS-A and histamine. In the whole experiment it can fight guinea pig asthma caused by SRS-A or histamine.