充血性心衰(CHF)有交感神经系统(SNS)的慢性激活。标志SNS活性的血浆去甲肾上腺素(NE)水平与CHF的严重程度呈正比。经β-肾上腺素能通路SNS的活力增加,被认为给衰竭的心脏提供了应激的变力和变时功能的支持,但也带来了一些不利的影响。 CHF是众所周知的临床综合征,它的病理生理学格外复杂。在研究CHF时,不断地发现其新的病理生理学改变,而这些改变对疾病过程的确切影响还很不清楚。 Congestive heart failure (CHF) has chronic activation of the sympathetic nervous system (SNS). Plasma norepinephrine (NE) levels, which signify SNS activity, are directly proportional to the severity of CHF. The increased viability of the β-adrenergic pathway, SNS, is thought to support the failing heart by providing stress-devaluing and time-varying functions but also with some detrimental effects. CHF is a well-known clinical syndrome whose pathophysiology is extraordinarily complicated. When studying CHF, new pathophysiological changes are constantly discovered, and the exact impact of these changes on the course of the disease is still unclear.