心痛定对慢性肺原性心脏病肺循环血液动力学的影响

来源 :湖北医药导报 | 被引量 : 0次 | 上传用户:L530798540
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目前有钙拮抗剂心痛定(Nifedipine,Nf)在缺氧情况下,可使肺动脉痉挛减轻的报告。与此相反,也有人报告心痛定会使肺动脉压升高,出现右心功能不全症状。本文作者乃进一步研究这个问题,特对慢性稳定状态的肺心病13例投给心痛定,进行观察。这13例中,皆无右心功能不全症状,并可除外高血压病、瓣膜病、心绞痛及心肌梗塞等病史。其基础疾病有慢性阻塞性肺疾病6例,肺结核后遗症6例,肺纤维化1例。年龄14~72岁(平均51.8±16.5岁),男11例,女2例。经导管测定并计算全肺血管阻 There are currently reports that the calcium antagonist nifedipine (Nf) reduces pulmonary vasospasm in the absence of oxygen. In contrast, there are also reports of heartache will make pulmonary arterial pressure, right heart failure symptoms appear. The author of this article is to further study this issue, especially for chronic stable pulmonary heart disease in 13 cases given to heartache, were observed. In these 13 cases, there is no symptoms of right ventricular dysfunction, and may exclude hypertension, valvular disease, angina and myocardial infarction and other medical history. The underlying diseases are chronic obstructive pulmonary disease in 6 cases, tuberculosis sequelae in 6 cases, 1 case of pulmonary fibrosis. Aged 14 to 72 years (mean 51.8 ± 16.5 years), 11 males and 2 females. The catheter was measured and calculated pulmonary vascular resistance
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