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目的探讨腹腔镜手术与开腹手术对卵巢囊肿患者卵巢储备功能及免疫功能的影响。方法选取卵巢囊肿患者84例,根据治疗方式分为两组,每组42例。对照组予以经腹卵巢囊肿剥除术,观察组予以腹腔镜卵巢囊肿剔除术。比较两组术后免疫功能和卵巢储备功能。结果术后3 d,两组免疫球蛋白M、免疫球蛋白A水平比较,差异未见统计学意义(P>0.05);观察组免疫球蛋白G水平高于对照组,差异有统计学意义(P<0.05)。术后6个月观察组促卵泡激素、抗苗勒管激素水平低于对照组,雌二醇水平高于对照组,差异有统计学意义(P<0.05)。结论与开腹手术比较,腹腔镜手术治疗卵巢囊肿,可减少对患者的卵巢储备功能和免疫功能影响。
Objective To investigate the effects of laparoscopic surgery and laparotomy on ovarian reserve and immune function in patients with ovarian cyst. Methods Eighty-four patients with ovarian cysts were selected and divided into two groups according to the treatment methods, 42 cases in each group. The control group was transabdominal ovarian cyst excision, the observation group was laparoscopic ovarian cyst excision. The postoperative immune function and ovarian reserve function were compared between the two groups. Results There was no significant difference in immunoglobulin M and immunoglobulin A levels between the two groups 3 d after operation (P> 0.05). The immunoglobulin G level in the observation group was significantly higher than that in the control group (P <0.05) P <0.05). The levels of follicle-stimulating hormone and anti-Mullerian hormone in the observation group were lower than those in the control group at 6 months after operation, and the levels of estradiol in the observation group were higher than those in the control group (P <0.05). Conclusion Compared with open surgery, laparoscopic surgery for ovarian cysts can reduce the ovarian reserve function and immune function in patients.