总结5例肺移植术后旱期发生严重原发性移植物功能丧失患者,应用体外膜肺氧合联合持续肾脏替代治疗救治的护理经验。护理要点:严密血流动力学监测和保持低血容量状态,呼吸功能监测及气道管理,维持血管通路的通畅,凝血功能监测和早期活动。4例好转出院,1例成功拔除体外膜肺氧合后行维持性血液透析治疗。 Summarize the nursing experience of 5 cases of patients with severe primary graft loss during the dry period after lung transplantation and the treatment of extracorporeal membrane lung oxygenation combined with continuous renal replacement therapy. Nursing highlights: Tight hemodynamic monitoring and maintenance of hypovolemia, respiratory monitoring and airway management, maintenance of vascular access, monitoring of coagulation and early activity. 4 patients were discharged and 1 patient was successfully treated with maintenance hemodialysis after extubation of pulmonary oxygen.