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为研究预防ＰＴＡ后再狭窄的有效中药，本实验于杂种犬观察了川芎嗪和阿司匹林对犬血小板聚集和对ＰＴＲＡ前后血小板聚集率变化的影响。结果显示，川芎嗪可显著抑制血小板聚集（Ｐ＜０．０１），降低ＰＴＲＡ对血小板功能变化的影响，致ＰＴＲＡ后血小板聚集率升高不显著（Ｐ＞０．０５）。表明川芎嗪可能是一种有效的预防ＰＴＡ后再狭窄的药物。
In order to study effective Chinese medicine for prevention of restenosis after PTA, the effects of tetramethylpyrazine and aspirin on platelet aggregation and platelet aggregation rate before and after PTRA were observed in the mongrel dogs. The results showed that tetramethylpyrazine can significantly inhibit platelet aggregation (P <0.01), and reduce the effect of PTRA on platelet function changes, resulting in no significant increase in platelet aggregation rate after PTRA (P> 0.05). It shows that tetramethylpyrazine may be an effective drug for preventing restenosis after PTA.