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14例眼肌麻痹患者,年龄16～52岁,平均37岁,男女各7例.静脉内给予~(99m)Tc-HMPAO 555MBq 1小时后显像.检查在暗室内进行,病人安静闭眼.全部患者同时进行CT和/或MRI检查.检查结果14例HMPAO脑显像中,8例出现局部灌注减低;3例为双顶-枕叶灌注减低,2例为左顶叶缺损(其中1例伴有右颞叶病变),2例为枕叶灌注减低,1例为额叶中部明显灌注减低.这8例中,有6例肢体运动减弱,而正常的6例中无1例肢体运动减弱.CT或MRI排除了局限性病变,11例患者有普遍的脑萎缩,4例MRI显示左顶枕叶有灰、白质信号强度颠倒.本文结果表明:眼肌麻痹患者脑rCBF(局部脑血流量)的改变既出现在仅有视觉受损的患者,也出现在中枢神经系统受损的患者.脑视皮质的灌注减
14 cases of ophthalmoplegia, aged from 16 to 52 years old, average 37 years old, each of 7 males and females.Intravenous ~ (99m) Tc-HMPAO 555MBq was given after 1 hour for imaging.Inspection was performed in the dark room and the eyes were closed quietly. All patients underwent simultaneous CT and / or MRI examination.Results In 14 cases of HMPAO brain imaging, there were 8 cases of local perfusion reduction, 3 cases of biparietal-occipital lobe perfusion reduction and 2 cases of left-sided parietal defect (1 case Accompanied by right temporal lobe lesions), 2 cases of occipital lobe perfusion decreased, 1 case of central frontal lobe was significantly reduced perfusion.Of these 8 cases, 6 cases of limb movement decreased, while the normal 6 cases, 1 case of limb movement was weakened CT or MRI ruled out the limitations of lesions, 11 patients had general brain atrophy, 4 cases of MRI showed the left upper occipital lobe gray, white matter signal intensity reversed.The results show that: ophthalmoplegia in patients with rCBF (regional cerebral blood flow ) Changes both in patients with only visual impairment and also in patients with impaired central nervous system