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目的了解染色体正常的男性无精子症患者的发病情况,探讨其病因和诊断、处理。方法入选染色体正常的无精子症患者212例,从年龄、职业、身高、体重、腮腺炎病史、棉籽油服用史、睾丸大小、激素水平、睾丸活检等15个方面分析总结流行病学和临床资料。结果在男性无精子症病因中,腮腺炎病史、棉籽油服用史、附睾炎史所占比例较高。在睾丸体积<12ml且FSH明显升高患者,睾丸活检未发现有成熟精子。结论预防腮腺炎的发生,避免食用棉籽油和预防附睾炎发生可以减少部分无精子症的发生。睾丸大小、质地与性激素水平对临床判断无精子症的类别有重要的意义。
Objective To understand the incidence of male patients with azoospermia normal chromosomes, to explore the etiology and diagnosis and treatment. Methods A total of 212 patients with normal azoospermia were enrolled in this study. Epidemiology and clinical data were analyzed from 15 aspects of age, occupation, height, weight, history of mumps, history of cottonseed oil, testicular size, hormone level and testicular biopsy . Results in the male azoospermia etiology, history of mumps, cottonseed oil taking history, a higher proportion of epididymitis history. In testicular volume <12ml and FSH was significantly elevated in patients with testicular biopsy found no mature sperm. Conclusion Prevention of mumps, avoid consumption of cottonseed oil and prevent the occurrence of epididymitis can reduce the incidence of some azoospermia. Testicular size, texture and sex hormone levels have important implications for the clinical classification of azoospermia.