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对２７例食管腺癌和同期确诊的２６５例食管鳞癌进行比较分析。二者男女比例、平均年龄相似。癌肿发生部位：腺癌大多数发生在下段，少数在中段；鳞癌半数以上发生在中段，近３０％在下段，近２０％在上段。临床症状中吞咽不畅感及胸骨后疼痛腺癌明显少于鳞癌；胃镜下形态腺癌肿块型多于鳞癌，而肿块浸润型少于鳞癌。以上资料经统计学处理有显著性差异。提示食管腺癌的生长方式和鳞癌有所不同，及可能存在和鳞癌不同的致病因素。
A comparative analysis of 27 cases of esophageal adenocarcinoma and 265 cases of esophageal squamous cell carcinoma diagnosed at the same time. The ratio of men and women and the average age are similar. Location of cancer: most of the adenocarcinomas occur in the lower part and a few in the middle part; more than half of the squamous cancers occur in the middle part, nearly 30% in the lower part, and nearly 20% in the upper part. The clinical symptoms of poor swallowing and poststernal pain were significantly less than those of squamous cell carcinoma. The endoscopic appearance of adenocarcinoma was more than that of squamous cell carcinoma. The infiltrative type of tumor was less than squamous cell carcinoma. The above data have statistically significant differences. It suggests that the growth pattern of esophageal adenocarcinoma is different from that of squamous cell carcinoma, and there may be different pathogenic factors from squamous cell carcinoma.