论文部分内容阅读
以年龄25～36岁的健康男子各5名为研究对象,给药方法:千金藤碱(CE)按1mg/kg体重于早晨空腹服下;对照药小柴胡汤(6.0g)在晨起空腹时顿服;角鲨烯制剂(6片)亦在晨起空腹时顿服。采血测定并比较诱导产生干扰素(IFN)的种类、IFN血中浓度的变化及临床药理学特性。采血时间及方法:CE的采血时间为服药前、服药1、2、4、6、8小时后,小柴胡汤与角鲨烯制剂的采血时间与CE略有不同。三种制剂的采血方法、血清分
Five healthy men aged 25-36 years old were selected as subjects to be studied. The method of administration was as follows: Cetrandrine (CE) was administered at 1 mg/kg body weight in the morning on an empty stomach; the control drug Xiao Chai Hu Tang (6.0 g) was given an empty stomach in the morning. Dayton clothing; Squalene preparations (6 tablets) were also served in the morning when fasting. Blood sampling was performed to determine and compare the type of interferon (IFN) produced, the change in the concentration of IFN blood, and clinical pharmacological characteristics. Blood collection time and method: CE blood collection time is 1,2,4,6,8 hours after taking the drug. The sampling time of Xiao Chai Hu Tang and squalene is slightly different from that of CE. Blood preparation method and serum concentration of three preparations