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探讨急性脑梗死与脑出血病人血浆甲状腺激素（ＴＨ）的变化及其临床意义．方法：应用放射免疫分析法测定６８例急性脑梗死与脑出血病人和５６例健康人（对照组）的血浆ＴＨ含量．结果：急性脑梗死和脑出血病人血浆Ｔ３／ＦＴ３含量测定（１．１８±０．４１）／ｎｍｏｌ／Ｌ／（２．９０±１．１２）ｐｍｏｌ／Ｌ、（１．０４±０．３９）ｎｍｏｌ／Ｌ／（２．８３±１．３６）ｐｍｏｌ／Ｌ明显低于对照组（１．９８±０．５１）ｎｍｏｌ／Ｌ，Ｐ＜０．０１／（６．３７±１．３１），Ｐ＜０．００１；死亡组Ｔ３／ＦＴ３水平与非死亡组Ｔ３／ＦＴ３水平相比较有显著差异（Ｐ＜０．０５／Ｐ＜０．０１）．结论：ＴＨ参与了急性脑梗死和脑出血病人的病理生理过程，监测急性脑梗死和脑出血病人的血浆ＴＨ水平可作为反映病情程度和评估预后的一项参考指标。
To investigate the changes of plasma thyroid hormone (TH) in patients with acute cerebral infarction and intracerebral hemorrhage and its clinical significance. Methods: Radioimmunoassay was used to determine plasma TH content in 68 patients with acute cerebral infarction and cerebral hemorrhage and 56 healthy controls (control group). Results: The levels of plasma T3 / FT3 in acute cerebral infarction and intracerebral hemorrhage were (1.18 ± 0.41) / nmol / L / (2.90 ± 1.12) pmol / L, (1.04 ± 0.39 ) Was significantly lower than that of the control group (1.98 ± 0.51 nmol / L, P <0.01 / (6.37 ± 1.31) nmol / L / (2.83 ± 1.36) pmol / , P <0.001. There was significant difference between T3 / FT3 level in death group and T3 / FT3 level in non-death group (P <0.05 / P <0.01). Conclusion: TH is involved in the pathophysiology of acute cerebral infarction and intracerebral hemorrhage. Monitoring plasma TH level in patients with acute cerebral infarction and cerebral hemorrhage can be used as a reference index to reflect the severity of the disease and assess the prognosis.