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妊娠期感染梅毒或梅毒患者合并妊娠称为妊娠梅毒。其发病率呈上升趋势,妊娠梅毒流行与孕妇经济收入水平、文化层次、年龄有关。梅毒螺旋体可感染胎盘而发生流产﹑死胎﹑早产﹑死产等各种妊娠不良结局,并可通过母婴垂直传播给胎儿,发生胎传梅毒。通过产前检查和梅毒筛查、积极治疗等综合干预,可使妊娠梅毒母婴传播阻断的成功率达到99.1%。妊娠梅毒越早治疗,不良妊娠结局及新生儿先天梅毒发生率越低;确诊时血清抗体滴度与妊娠不良结局的发生率及先天梅毒发病率均有较显著的相关性;梅毒孕妇是否终止妊娠,需对血清滴度、孕周、病期、规范治疗多项指标综合评估后决定。胎儿及新生儿应有恰当的评估和足够的随访,有胎传梅毒风险的新生儿需治疗。
Pregnancy syphilis or syphilis infection in patients with pregnancy known as pregnancy syphilis. Its incidence is on the rise, and the prevalence of syphilis in pregnant women is related to their level of income, cultural level and age. Treponema pallidum placenta infection can occur abortion, stillbirth, preterm birth, stillbirth and other adverse pregnancy outcomes, and vertical transmission through the mother and fetus to the fetus, the occurrence of fetal syphilis. Through the prenatal care and syphilis screening, active treatment and other comprehensive intervention, the success rate of pregnancy to prevent syphilis mother-to-child transmission of 99.1%. The sooner pregnancy treatment of syphilis, adverse pregnancy outcomes and neonatal congenital syphilis the lower the incidence of; serum antibody titer at diagnosis and the incidence of adverse pregnancy outcomes and congenital syphilis incidence have a more significant correlation; syphilis pregnant women whether to terminate the pregnancy , The need for serum titer, gestational age, stage of disease, standardized treatment of a number of comprehensive evaluation of the decision. Fetal and neonatal should be properly assessed and adequate follow-up, neonatal syphilis risk of fetal treatment.