目的:了解个旧市海洛因依赖者HCV及HIV的感染情况,并与5年前的感染情况作对照分析,评估海洛因依赖者HCV及HIV的感染原因及趋势。方法:抽取同期住院的吸毒者入院次日空腹外周静脉血,分为两个组(烫吸组和静脉注射组),采用ELISA法检测抗HCV及HIV(1+2)的阳性率,观察两组间的差异并与5年前的资料进行比较分析。结果:静脉注射组抗HCV及抗HIV的双重阳性率明显高于烫吸组,分别是79.2%、54.2%、25.0%与36.3%、25.9%、4.0%,与5年前比较,有极显著的差异性。结论:HCV、HIV感染率比5年前剧增。静脉注射毒品仍是HCV、HIV感染的直接相关因素,吸毒者交叉使用注射器是造成感染的重要原因。性乱造成HCV及HIV感染率逐年上升。因此,预防宜采取综合配套措施,以减缓HCV及HIV在吸毒者中蔓延及阻止向健康人群的传播。 Objective: To understand the infection status of HCV and HIV among heroin addicts in Gejiu City and compare the infection status with that before 5 years ago to evaluate the causes and trends of HCV and HIV infection in heroin addicts. Methods: Fasting peripheral venous blood was collected on the next day after admission. Drug abusers were divided into two groups (hot-sucking group and intravenous group). The positive rate of anti-HCV and HIV (1 + 2) Differences between groups were compared with data from five years ago. Results: The positive rates of anti-HCV and anti-HIV in intravenous injection group were significantly higher than those in the scald suction group (79.2%, 54.2%, 25.0% and 36.3%, 25.9% and 4.0%, respectively) The difference. Conclusion: The prevalence of HCV and HIV infection has risen more than 5 years ago. Intravenous drug use is still the direct cause of HCV and HIV infection. Cross-use of syringes by drug users is an important cause of infection. Sexually transmitted diseases cause HCV and HIV infection rates increased year by year. Therefore, preventive measures should be taken comprehensively to mitigate the spread of HCV and HIV among drug users and to prevent their spread to healthy people.