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目的:通过临床病历探讨单份量的双米合并丙酸睾丸酮用于妊娠14～18周引产的可行性。方法:将妊娠14～18周要求药物引产者214例分为两组采用单份量的双米加用丙酸睾丸酮的方法引产,为观察组110例;采用双份剂量的双米的方法引产为对照组104例。结果:观察组有2例失败,成功率为98.18%,对照组成功率为100%,2组无显著差异P>0.05,两组孕14～16周产程明显短于孕17～18周,用药副反应观察组占12.5%对照组占44.23%,差异显著P<0.01。结论:单份剂量双米合并丙酸睾丸酮用于14～18周引产与双份剂量双米效果相同,且副作用小,更适合于妊娠≤16周者。
OBJECTIVE: To investigate the feasibility of single-dose, two-meter combined testosterone propionate for induction of labor during 14-18 weeks of gestation through clinical records. Methods: The 14 to 18 weeks of gestation induced drug induced abortion were divided into two groups of 214 patients using single dose of two meters plus testosterone propionate induction of labor for the observation group of 110 cases; double dose of double-meter method of induction of labor Control group of 104 cases. Results: In the observation group, 2 patients failed, the success rate was 98.18%, the control group success rate was 100%, there was no significant difference between the two groups P> 0.05. The two groups of 14 to 16 weeks of pregnancy was significantly shorter than the gestational 17 to 18 weeks, Response observation group accounted for 12.5% of the control group accounted for 44.23%, the difference was significant P <0.01. Conclusion: A single dose of two meters combined with testosterone propionate for 14 to 18 weeks induction of labor and double doses of double the same effect, and the side effects of small, more suitable for pregnancy ≤ 16 weeks were.