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目的探索云南山区血吸虫病患者感染度与症状体征之间的关系。方法在高原峡谷型血吸虫病流行区,用集卵孵化法和改良加藤法对5～65岁居民进行粪便检查,并作虫卵定量记数,计算EPG,同时,对查出的全部患者进行体检,观察患者的感染度与症状体征之间的关系。结果调查区居民的粪检阳性率为37.57%,患者EPG(x±s)为26.18±30.96;85.19%的感染者没有自觉症状和体征,有症状体征的患者存在于各个EPG分级组,当EPG≥64时,患者的症状体征发生率明显升高;肝肿大、腹泻、脓血便和脾肿大发生率依次为9.52%、5.82%、4.76%和2.12%;肝肿大发生率随年龄的增大呈上升趋势,但没有性别差异。结论云南山区居民血吸虫感染率较高,但感染度不高,在粪检阳性的感染者中,有症状体征者仅占少数,症状体征发生率随患者感染度的升高而升高,在几种常见的症状体征中,肝肿大发生率最高,且与年龄有关,但与性别无关。
Objective To explore the relationship between schistosomiasis prevalence and symptoms and signs in mountainous areas of Yunnan. Methods In the prevalence area of schistosomiasis endemic to plateau, stool samples were collected from 5 to 65-year-old residents by egg hatching method and modified Kato’s method. Quantitation of the number of eggs was performed to calculate EPG. At the same time, all the patients were examined , Observe the relationship between the patient’s degree of infection and symptoms and signs. Results The positive rate of fecal examination was 37.57% and the EPG (x ± s) of patients was 26.18 ± 30.96. There were no symptoms and signs in 85.19% of infected persons. Patients with symptomatic signs were present in all EPG grading groups. When EPG The incidence rate of symptoms and signs of patients was significantly higher than or equal to 64, the rates of hepatomegaly, diarrhea, pus and bloody spasm were 9.52%, 5.82%, 4.76% and 2.12% respectively. The incidence of hepatomegaly was significantly different with age There is an upward trend but no gender difference. Conclusion The prevalence of schistosomiasis in mountainous areas of Yunnan Province is high, but the infection rate is not high. Among the infected persons with positive stool tests, only a few have symptoms and signs, and the incidence of symptoms and signs increases with the infection of patients, Of the common symptoms and signs, the highest incidence of hepatomegaly, and age-related, but has nothing to do with gender.