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我院自1982年起术前对25例中晚期上颌、腮腺区恶性肿瘤行动脉化疗同时加~(60)钴外照射合并手术综合治疗的研究,结果术前肿瘤完全消失和肿瘤缩小超过50％各10例,有效率为80％,休息4周,25例均经手术切除,术后病理阴性5例。本文还对动脉化疗的方法、解剖学依据、有效药物的选择和配伍作了简要介绍,并结合文献对动脉化疗与放疗综合应用的协同作用机理作了粗浅的讨论。
In our hospital from the beginning of 1982, 25 cases of advanced malignant maxillofacial and parotid gland tumors were treated with arterial chemoembolization plus 60 cobalt external irradiation combined with surgical treatment. The results showed that the tumor disappeared completely and the tumor shrinkage exceeded 50%. In 10 cases, the effective rate was 80%. After 4 weeks of rest, 25 cases were surgically removed and 5 cases were pathologically negative. This article also gives a brief introduction to the arterial chemotherapy methods, anatomical basis, selection and compatibility of effective drugs, and makes a shallow discussion on the synergistic mechanism of arterial chemotherapy and radiotherapy.